Ankylosing Spondylitis

Ankylosing spondylitis symptoms typically develop gradually and may vary from person to person. Early recognition of these symptoms is important for timely treatment:

• Lower back and hip pain that worsens with rest and improves with activity
• Morning stiffness lasting more than 30 minutes
• Pain and stiffness that improve with exercise and worsen at night
• Fatigue from chronic inflammation
• Reduced range of motion in your spine
• Chest pain and difficulty taking deep breaths
• Eye inflammation (uveitis) causing redness and pain
• Joint pain in shoulders, knees, or ankles

The exact cause of ankylosing spondylitis isn’t fully understood, but research shows it involves a combination of genetic and environmental factors. Most people with AS carry a gene called HLA-B27, though having this gene doesn’t guarantee you’ll develop the condition.

Key risk factors include:

• Age: Symptoms typically begin between ages 17-35
• Gender: Men are diagnosed 2-3 times more often than women
• Genetics: Having the HLA-B27 gene increases risk significantly
• Family history: Having a parent or sibling with AS increases your risk
• Other conditions: Inflammatory bowel disease or psoriasis may increase risk

Diagnosing ankylosing spondylitis requires a comprehensive evaluation by our specialists, as early symptoms can be similar to other back conditions. Our diagnostic process includes:

Physical Examination: We assess your spine flexibility, posture, and range of motion, and check for tenderness in your sacroiliac joints and spine.

Medical History: We discuss your symptoms, family history, and how your pain responds to rest and activity.

Blood Tests: We test for the HLA-B27 gene and markers of inflammation such as ESR and CRP levels.

Advanced Imaging: X-rays can show changes in joints and spine, while MRI scans can detect early inflammation before structural changes occur.

Early diagnosis is crucial because prompt treatment can help prevent or slow the progression of spinal fusion and maintain your mobility.

Don’t ignore persistent back pain, especially if you’re a young adult. You should schedule an appointment with our team if you experience:

• Chronic lower back pain lasting more than 3 months, especially if it began before age 40
• Back pain and stiffness that’s worse in the morning or after periods of inactivity
• Pain that improves with exercise or activity but worsens with rest
• Gradual loss of flexibility in your spine
• Pain that disrupts your sleep or wakes you up at night
• Eye inflammation with redness, pain, or sensitivity to light
• Family history of AS combined with any back pain symptoms

Early intervention can make a significant difference in managing AS and preventing complications. Our specialists can provide an accurate diagnosis and create a treatment plan tailored to your specific needs.